1. Discovery of a 2′-fluoro-2′-C-methyl C-nucleotide HCV polymerase inhibitor and a phosphoramidate prodrug with favorable properties. Issue 8 (15th April 2017) Authors: Kirschberg, Thorsten A.; Metobo, Sammy; Clarke, Michael O.; Aktoudianakis, Vangelis; Babusis, Darius; Barauskas, Ona; Birkus, Gabriel; Butler, Thomas; Byun, Daniel; Chin, Gregory; Doerffler, Edward; Edwards, Thomas E.; Fenaux, Martijn; Lee, Rick; Lew, Willard; Mish, Michael R.; Murakami, Eisuke; ... Journal: Bioorganic & medicinal chemistry letters Issue: Volume 27:Issue 8(2017) Page Start: 1840 Record Type: Journal Article View Content: Available online (eLD content is only available in our Reading Rooms) ↗
2. Discovery of β-d-2′-deoxy-2′-α-fluoro-4′-α-cyano-5-aza-7, 9-dideaza adenosine as a potent nucleoside inhibitor of respiratory syncytial virus with excellent selectivity over mitochondrial RNA and DNA polymerases. Issue 12 (15th June 2015) Authors: Clarke, Michael O.; Mackman, Richard; Byun, Daniel; Hui, Hon; Barauskas, Ona; Birkus, Gabriel; Chun, Byoung-Kwon; Doerffler, Edward; Feng, Joy; Karki, Kapil; Lee, Gary; Perron, Michel; Siegel, Dustin; Swaminathan, Swami; Lee, William Journal: Bioorganic & medicinal chemistry letters Issue: Volume 25:Issue 12(2015) Page Start: 2484 Record Type: Journal Article View Content: Available online (eLD content is only available in our Reading Rooms) ↗