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- De Matteo, Marilenia [remove] 2
- 572 2
- Bioorganic chemistry -- Periodicals 2
- Pharmaceutical chemistry -- Periodicals 2
- CAM capsid assembly modulators -- HBV hepatitis B virus -- SBA sulfamoylbenzammide -- CHB chronic hepatitis B -- NUCs nuocles(t)ide analogues -- HCC hepatocellular carcinoma -- HBcAg and Cp core protein -- pgRNA pregenomic RNA -- NCE new chemical entities -- cccDNA closed circular DNA -- NHS 40% human serum -- HP human hepatocytes -- qPCR polymerase chain reaction -- HBD hydrogen bond donor -- HBA hydrogen bond acceptor -- CYP450 cytochrome P450 -- IV intravenous -- PO per os -- Clp plasma clearance -- Vd volume of distribution -- τ1/2 plasma half-life -- F% oral bioavailability -- AUC area under the curve -- h-ERG human Ether-à-go-go-Related Gene -- BID bis in die -- PEG polyethylene glycol 1
- Chronic hepatitis B -- Hepatic B virus (HBV) -- Capsid assembly modulator (CAM) 1
- H3K9 methylation -- G9a -- GLP -- Skeletal muscle regeneration -- Duchenne muscle dystrophy 1
- PTM post-translational modifications -- HMT histone methyl transferases -- EHMT2 euchromatic histone N-methyltransferase 2 -- EHMT1 euchromatic histone-lysine N-methyltransferase 1 -- KMTs lysine methyltransferases -- SAM S-adenosyl-l-Met -- H3K9m1 mono-methylation of Lys 9 on histone H3 -- H3K9m2 di-methylation of Lys 9 on histone H3 -- MyHC+ Myosin Heavy Chain positive 1