1. Phase I study of PF‐04895162, a Kv7 channel inhibitor, reveals unexpected hepatotoxicity in healthy subjects, but not rats or monkeys: clinical evidence of disrupted bile acid homeostasis. Issue 1 (11th February 2019) Authors: Aleo, Michael D.; Aubrecht, Jiri; D. Bonin, Paul; Burt, Deborah A.; Colangelo, Jennifer; Luo, Lina; Schomaker, Shelli; Swiss, Rachel; Kirby, Simon; C. Rigdon, Greg; Dua, Pinky Journal: Pharmacology research & perspectives Issue: Volume 7:Issue 1(2019) Page Start: n/a Record Type: Journal Article View Content: Available online (eLD content is only available in our Reading Rooms) ↗
2. Phase I study of PF‐04895162, a Kv7 channel opener, reveals unexpected hepatotoxicity in healthy subjects, but not rats or monkeys: clinical evidence of disrupted bile acid homeostasis. Issue 1 (11th February 2019) Authors: Aleo, Michael D.; Aubrecht, Jiri; D. Bonin, Paul; Burt, Deborah A.; Colangelo, Jennifer; Luo, Lina; Schomaker, Shelli; Swiss, Rachel; Kirby, Simon; C. Rigdon, Greg; Dua, Pinky Journal: Pharmacology research & perspectives Issue: Volume 7:Issue 1(2019) Page Start: n/a Record Type: Journal Article View Content: Available online (eLD content is only available in our Reading Rooms) ↗