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Author/Creator Cleary, Yumi

1. A phase 1 healthy male volunteer single escalating dose study of the pharmacokinetics and pharmacodynamics of risdiplam (RG7916, RO7034067), a SMN2 splicing modifier. Issue 1 (16th November 2018)

Authors:
Sturm, Stefan; Günther, Andreas; Jaber, Birgit; Jordan, Paul; Al Kotbi, Nada; Parkar, Nikhat; Cleary, Yumi; Frances, Nicolas; Bergauer, Tobias; Heinig, Katja; Kletzl, Heidemarie; Marquet, Anne; Ratni, Hasane; Poirier, Agnès; Müller, Lutz; Czech, Christian; Khwaja, Omar
Journal:
British journal of clinical pharmacology
Issue:
Volume 85:Issue 1(2019)
Page Start:
181
Record Type:
Journal Article
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2. Clinical Drug–Drug Interactions Through Cytochrome P450 3A (CYP3A) for the Selective ALK Inhibitor Alectinib. Issue 3 (28th September 2016)

Authors:
Morcos, Peter N.; Cleary, Yumi; Guerini, Elena; Dall, Georgina; Bogman, Katrijn; De Petris, Luigi; Viteri, Santiago; Bordogna, Walter; Yu, Li; Martin‐Facklam, Meret; Phipps, Alex
Journal:
Clinical pharmacology in drug development
Issue:
Volume 6:Issue 3(2017)
Page Start:
280
Record Type:
Journal Article
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3. Development of a physiologically based pharmacokinetic model for mefloquine and its application alongside a clinical effectiveness model to select an optimal dose for prevention of malaria in young Caucasian children. Issue 1 (5th November 2018)

Authors:
Johnson, Trevor N.; Cleary, Yumi; Parrott, Neil; Reigner, Bruno; Smith, James R.; Toovey, Stephen
Journal:
British journal of clinical pharmacology
Issue:
Volume 85:Issue 1(2019)
Page Start:
100
Record Type:
Journal Article
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5. Model‐Based Assessments of CYP‐Mediated Drug–Drug Interaction Risk of Alectinib: Physiologically Based Pharmacokinetic Modeling Supported Clinical Development. Issue 3 (27th December 2017)

Authors:
Cleary, Yumi; Gertz, Michael; Morcos, Peter N.; Yu, Li; Youdim, Kuresh; Phipps, Alex; Fowler, Stephen; Parrott, Neil
Journal:
Clinical pharmacology & therapeutics
Issue:
Volume 104:Issue 3(2018)
Page Start:
505
Record Type:
Journal Article
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6. Model‐Based Drug–Drug Interaction Extrapolation Strategy From Adults to Children: Risdiplam in Pediatric Patients With Spinal Muscular Atrophy. Issue 6 (1st September 2021)

Authors:
Cleary, Yumi; Gertz, Michael; Grimsey, Paul; Günther, Andreas; Heinig, Katja; Ogungbenro, Kayode; Aarons, Leon; Galetin, Aleksandra; Kletzl, Heidemarie
Journal:
Clinical pharmacology & therapeutics
Issue:
Volume 110:Issue 6(2021)
Page Start:
1547
Record Type:
Journal Article
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7. Physiologically Based Pharmacokinetic Model Qualification and Reporting Procedures for Regulatory Submissions: A Consortium Perspective. Issue 1 (2nd February 2018)

Authors:
Shebley, Mohamad; Sandhu, Punam; Emami Riedmaier, Arian; Jamei, Masoud; Narayanan, Rangaraj; Patel, Aarti; Peters, Sheila Annie; Reddy, Venkatesh Pilla; Zheng, Ming; de Zwart, Loeckie; Beneton, Maud; Bouzom, Francois; Chen, Jun; Chen, Yuan; Cleary, Yumi; Collins, Christiane; Dickinson, Gemma L.; ...
Journal:
Clinical pharmacology & therapeutics
Issue:
Volume 104:Issue 1(2018)
Page Start:
88
Record Type:
Journal Article
View Content:
Available online (eLD content is only available in our Reading Rooms) ↗