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Author/Creator Christensen, James G.

1. Design and evaluation of achiral, non-atropisomeric 4-(aminomethyl)phthalazin-1(2H)-one derivatives as novel PRMT5/MTA inhibitors. (1st October 2022)

Authors:
Smith, Christopher R.; Aranda, Ruth; Christensen, James G.; Engstrom, Lars D.; Gunn, Robin J.; Ivetac, Anthony; Ketcham, John M.; Kuehler, Jon; David Lawson, J.; Marx, Matthew A.; Olson, Peter; Thomas, Nicole C.; Wang, Xiaolun; Waters, Laura M.; Kulyk, Svitlana
Journal:
Bioorganic & medicinal chemistry
Issue:
Volume 71(2022)
Page Start:
Record Type:
Journal Article
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2. First-in-Human Phase I/IB Dose-Finding Study of Adagrasib (MRTX849) in Patients With Advanced KRASG12C Solid Tumors (KRYSTAL-1). Issue 23 (10th August 2022)

Authors:
Ou, Sai-Hong Ignatius; Jänne, Pasi A.; Leal, Ticiana A.; Rybkin, Igor I.; Sabari, Joshua K.; Barve, Minal A.; Bazhenova, Lyudmila; Johnson, Melissa L.; Velastegui, Karen L.; Cilliers, Cornelius; Christensen, James G.; Yan, Xiaohong; Chao, Richard C.; Papadopoulos, Kyriakos P.
Journal:
Journal of clinical oncology
Issue:
Volume 40:Issue 23(2022)
Page Start:
2530
Record Type:
Journal Article
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3. Fragment optimization and elaboration strategies – the discovery of two lead series of PRMT5/MTA inhibitors from five fragment hits. Issue 12 (27th September 2022)

Authors:
Smith, Christopher R.; Kulyk, Svitlana; Ahmad, Misbha Ud Din; Arkhipova, Valentina; Christensen, James G.; Gunn, Robin J.; Ivetac, Anthony; Ketcham, John M.; Kuehler, Jon; Lawson, J. David; Thomas, Nicole C.; Wang, Xiaolun; Marx, Matthew A.
Journal:
RSC medicinal chemistry
Issue:
Volume 13:Issue 12(2022)
Page Start:
1549
Record Type:
Journal Article
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4. Loss of CDKN2A expression is a frequent event in primary invasive melanoma and correlates with sensitivity to the CDK4/6 inhibitor PD0332991 in melanoma cell lines. (6th March 2014)

Authors:
Young, Richard J.; Waldeck, Kelly; Martin, Claire; Foo, Jung H.; Cameron, Donald P.; Kirby, Laura; Do, Hongdo; Mitchell, Catherine; Cullinane, Carleen; Liu, Wendy; Fox, Stephen B.; Dutton‐Regester, Ken; Hayward, Nicholas K.; Jene, Nicholas; Dobrovic, Alexander; Pearson, Richard B.; Christensen, J...
Journal:
Pigment cell & melanoma research
Issue:
Volume 27:Number 4(2014:Jul.)
Page Start:
590
Record Type:
Journal Article
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5. Metabolism, excretion and pharmacokinetics of [14C]crizotinib following oral administration to healthy subjects. (January 2015)

Authors:
Johnson, Theodore R.; Tan, Weiwei; Goulet, Lance; Smith, Evan B.; Yamazaki, Shinji; Walker, Gregory S.; O'Gorman, Melissa T.; Bedarida, Gabriella; Zou, Helen Y.; Christensen, James G.; Nguyen, Leslie N.; Shen, Zhongzhou; Dalvie, Deepak; Bello, Akintunde; Smith, Bill J.
Journal:
Xenobiotica
Issue:
Volume 45:Number 1(2015:Jan.)
Page Start:
45
Record Type:
Journal Article
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6. Mocetinostat for patients with previously treated, locally advanced/metastatic urothelial carcinoma and inactivating alterations of acetyltransferase genes. Issue 4 (20th December 2018)

Authors:
Grivas, Petros; Mortazavi, Amir; Picus, Joel; Hahn, Noah M.; Milowsky, Matthew I.; Hart, Lowell L.; Alva, Ajjai; Bellmunt, Joaquim; Pal, Sumanta K.; Bambury, Richard M.; O'Donnell, Peter H.; Gupta, Sumati; Guancial, Elizabeth A.; Sonpavde, Guru P.; Faltaos, Demiana; Potvin, Diane; Christensen, Ja...
Journal:
Cancer
Issue:
Volume 125:Issue 4(2019)
Page Start:
533
Record Type:
Journal Article
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7. Synergistic Effect of the γ‐Secretase Inhibitor PF‐03084014 and Docetaxel in Breast Cancer Models. (13th February 2013)

Authors:
Zhang, Cathy C.; Yan, Zhengming; Zong, Qing; Fang, Douglas D.; Painter, Cory; Zhang, Qin; Chen, Enhong; Lira, Maruja E.; John-Baptiste, Annette; Christensen, James G.
Journal:
Stem cells translational medicine
Issue:
Volume 2:Number 3(2013)
Page Start:
233
Record Type:
Journal Article
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