Search

Author/Creator Choo, Edna F.

1. Absorption, metabolism and excretion of cobimetinib, an oral MEK inhibitor, in rats and dogs. (2nd January 2017)

Authors:
Takahashi, Ryan H.; Ma, Shuguang; Yue, Qin; Kim-Kang, Heasook; Yi, Yijun; Ly, Justin; Boggs, Jason W.; Fettes, Alec; McClory, Andrew; Deng, Yuzhong; Hop, Cornelis E. C. A.; Khojasteh, S. Cyrus; Choo, Edna F.
Journal:
Xenobiotica
Issue:
Volume 47:Number 1(2017)
Page Start:
50
Record Type:
Journal Article
View Content:
Available online (eLD content is only available in our Reading Rooms) ↗

2. Assessment of OATP transporter‐mediated drug–drug interaction using physiologically‐based pharmacokinetic (PBPK) modeling – a case example. (20th November 2018)

Authors:
Chen, Yuan; Zhu, Rui; Ma, Fang; Mao, Jialin; Chen, Eugene C.; Choo, Edna F.; Sahasranaman, Srikumar; Liu, Lichuan
Journal:
Biopharmaceutics & drug disposition
Issue:
Volume 39:Number 9(2018:Dec.)
Page Start:
420
Record Type:
Journal Article
View Content:
Available online (eLD content is only available in our Reading Rooms) ↗

3. Design and synthesis of a biaryl series as inhibitors for the bromodomains of CBP/P300. Issue 1 (1st January 2018)

Authors:
Lai, Kwong Wah; Romero, F. Anthony; Tsui, Vickie; Beresini, Maureen H.; de Leon Boenig, Gladys; Bronner, Sarah M.; Chen, Kevin; Chen, Zhongguo; Choo, Edna F.; Crawford, Terry D.; Cyr, Patrick; Kaufman, Susan; Li, Yingjie; Liao, Jiangpeng; Liu, Wenfeng; Ly, Justin; Murray, Jeremy; Shen, Weichao; W...
Journal:
Bioorganic & medicinal chemistry letters
Issue:
Volume 28:Issue 1(2018)
Page Start:
15
Record Type:
Journal Article
View Content:
Available online (eLD content is only available in our Reading Rooms) ↗

4. Identification and profiling of GDC-0810 metabolites from admistration of a single oral dose of 14C GDC-0810 to intact and bile duct cannulated (BDC) rats. Issue 1 (January 2017)

Authors:
Zhang, Chenghong; Zhang, Donglu; Choo, Edna F.; DeMent, Kevin; Savage, Scott; Khojasteh, S. Cyrus
Journal:
Drug metabolism and pharmacokinetics
Issue:
Volume 32:Issue 1(2017)Supplement
Page Start:
S76
Record Type:
Journal Article
View Content:
Available online (eLD content is only available in our Reading Rooms) ↗

6. Preclinical Safety Assessment of a Highly Selective and Potent Dual Small-Molecule Inhibitor of CBP/P300 in Rats and Dogs. (April 2020)

Authors:
Katavolos, Paula; Cain, Gary; Farman, Cindy; Romero, F. Anthony; Magnuson, Steven; Ly, Justin Q.; Choo, Edna F.; Katakam, Anand Kumar; Andaya, Roxanne; Maher, Jonathan
Journal:
Toxicologic pathology
Issue:
Volume 48:Number 3(2020)
Page Start:
465
Record Type:
Journal Article
View Content:
Available online (eLD content is only available in our Reading Rooms) ↗