1. A Quantitative Modeling and Simulation Framework to Support Candidate and Dose Selection of Anti‐SARS‐CoV‐2 Monoclonal Antibodies to Advance Bamlanivimab Into a First‐in‐Human Clinical Trial. Issue 3 (17th November 2021) Authors: Chigutsa, Emmanuel; Jordie, Eric; Riggs, Matthew; Nirula, Ajay; Elmokadem, Ahmed; Knab, Tim; Chien, Jenny Y. Journal: Clinical pharmacology & therapeutics Issue: Volume 111:Issue 3(2022) Page Start: 595 Record Type: Journal Article View Content: Available online (eLD content is only available in our Reading Rooms) ↗
2. Development and Application of a Mechanistic Population Modeling Approach to Describe Abemaciclib Pharmacokinetics. (13th August 2020) Authors: Chigutsa, Emmanuel; Kambhampati, Siva Rama Prasad; Karen Sykes, Amanda; Posada, Maria M.; van der Walt, Jan‐Stefan; Turner, P. Kellie Journal: CPT: pharmacometrics & systems pharmacology Issue: Volume 9:Number 9(2020) Page Start: 523 Record Type: Journal Article View Content: Available online (eLD content is only available in our Reading Rooms) ↗
3. Exposure‐Response Modeling to Characterize the Relationship Between Ixekizumab Serum Drug Concentrations and Efficacy Responses at Week 12 in Patients With Moderate to Severe Plaque Psoriasis. (7th June 2018) Authors: Chigutsa, Emmanuel; Velez de Mendizabal, Nieves; Chua, Laiyi; Heathman, Michael; Friedrich, Stuart; Jackson, Kimberley; Reich, Kristian Journal: Journal of clinical pharmacology Issue: Volume 58:Number 11(2018) Page Start: 1489 Record Type: Journal Article View Content: Available online (eLD content is only available in our Reading Rooms) ↗
4. First‐in‐Human Study of Bamlanivimab in a Randomized Trial of Hospitalized Patients With COVID‐19. Issue 6 (16th October 2021) Authors: Chen, Peter; Datta, Gourab; Grace Li, Ying; Chien, Jenny; Price, Karen; Chigutsa, Emmanuel; Brown‐Augsburger, Patricia; Poorbaugh, Josh; Fill, Jeffrey; Benschop, Robert J.; Rouphael, Nadine; Kay, Ariel; Mulligan, Mark J.; Saxena, Amit; Fischer, William A.; Dougan, Michael; Klekotka, Paul; Nirula,... Journal: Clinical pharmacology & therapeutics Issue: Volume 110:Issue 6(2021) Page Start: 1467 Record Type: Journal Article View Content: Available online (eLD content is only available in our Reading Rooms) ↗
5. PK/PD modeling links accelerated resolution of COVID‐19‐related clinical symptoms to SARS‐CoV‐2 viral load reduction in patients following treatment with Bamlanivimab alone or Bamlanivimab and Etesevimab together. (5th April 2022) Authors: Ernest, C. Steven; Chien, Jenny Y.; Patel, Dipak R.; Chigutsa, Emmanuel Journal: CPT: pharmacometrics & systems pharmacology Issue: Volume 11:Number 6(2022) Page Start: 721 Record Type: Journal Article View Content: Available online (eLD content is only available in our Reading Rooms) ↗
6. Population Pharmacokinetics and Pharmacodynamics of the Neutralizing Antibodies Bamlanivimab and Etesevimab in Patients With Mild to Moderate COVID‐19 Infection. Issue 5 (24th September 2021) Authors: Chigutsa, Emmanuel; O'Brien, Lisa; Ferguson‐Sells, Lisa; Long, Amanda; Chien, Jenny Journal: Clinical pharmacology & therapeutics Issue: Volume 110:Issue 5(2021) Page Start: 1302 Record Type: Journal Article View Content: Available online (eLD content is only available in our Reading Rooms) ↗
7. Safety and efficacy of once-weekly basal insulin Fc in people with type 2 diabetes previously treated with basal insulin: a multicentre, open-label, randomised, phase 2 study. Issue 3 (March 2023) Authors: Frias, Juan; Chien, Jenny; Zhang, Qianyi; Chigutsa, Emmanuel; Landschulz, William; Syring, Kristen; Wullenweber, Paula; Haupt, Axel; Kazda, Christof Journal: Lancet Issue: Volume 11:Issue 3(2023) Page Start: 158 Record Type: Journal Article View Content: Available online (eLD content is only available in our Reading Rooms) ↗
8. Transformation Morphisms and Time-to-Extinction Analysis That Map Therapy Duration From Preclinical Models to Patients With Tuberculosis: Translating From Apples to Oranges. (28th November 2018) Authors: Magombedze, Gesham; Pasipanodya, Jotam G; Srivastava, Shashikant; Deshpande, Devyani; Visser, Marianne E; Chigutsa, Emmanuel; McIlleron, Helen; Gumbo, Tawanda Journal: Clinical infectious diseases Issue: Volume 67(2018)Supplement 3 Page Start: S349 Record Type: Journal Article View Content: Available online (eLD content is only available in our Reading Rooms) ↗