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Author/Creator Charman, Susan A.

1. Application of PBPK modeling to evaluate pharmacokinetic drug-drug interactions during the development of new antimalarial combination therapies. Issue 1 (January 2019)

Authors:
Abla, Nada; Almond, Lisa; Dickins, Maurice; Gobeau, Nathalie; Charman, Susan A.; Rowland-Yeo, Karen; El Gaaloul, Myriam; Barter, Zoe; Moehrle, Joerg; Wesche, David; Burrows, Jeremy
Journal:
Drug metabolism and pharmacokinetics
Issue:
Volume 34:Issue 1(2019)Supplement
Page Start:
S68
Record Type:
Journal Article
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2. Development of Diaminoquinazoline Histone Lysine Methyltransferase Inhibitors as Potent Blood‐Stage Antimalarial Compounds. Issue 10 (9th July 2014)

Authors:
Sundriyal, Sandeep; Malmquist, Nicholas A.; Caron, Joachim; Blundell, Scott; Liu, Feng; Chen, Xin; Srimongkolpithak, Nitipol; Jin, Jian; Charman, Susan A.; Scherf, Artur; Fuchter, Matthew J.
Journal:
ChemMedChem
Issue:
Volume 9:Issue 10(2014:Oct.)
Page Start:
2360
Record Type:
Journal Article
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3. First‐in‐man safety and pharmacokinetics of synthetic ozonide OZ439 demonstrates an improved exposure profile relative to other peroxide antimalarials. (10th January 2013)

Authors:
Moehrle, Joerg J.; Duparc, Stephan; Siethoff, Christoph; van, Paul L. M.; Craft, J. Carl; Arbe‐Barnes, Sarah; Charman, Susan A.; Gutierrez, Maria; Wittlin, Sergio; Vennerstrom, Jonathan L.
Journal:
British journal of clinical pharmacology
Issue:
Volume 75:Number 2(2013:Feb.)
Page Start:
535
Record Type:
Journal Article
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5. Progress in antischistosomal N, N′-diaryl urea SAR. Issue 3 (1st February 2018)

Authors:
Wu, Jianbo; Wang, Chunkai; Leas, Derek; Vargas, Mireille; White, Karen L.; Shackleford, David M.; Chen, Gong; Sanford, Austin G.; Hemsley, Ryan M.; Davis, Paul H.; Dong, Yuxiang; Charman, Susan A.; Keiser, Jennifer; Vennerstrom, Jonathan L.
Journal:
Bioorganic & medicinal chemistry letters
Issue:
Volume 28:Issue 3(2018)
Page Start:
244
Record Type:
Journal Article
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8. Synthesis and antimalarial evaluation of amide and urea derivatives based on the thiaplakortone A natural product scaffold. Issue 5 (10th December 2014)

Authors:
Schwartz, Brett D.; Skinner-Adams, Tina S.; Andrews, Katherine T.; Coster, Mark J.; Edstein, Michael D.; MacKenzie, Donna; Charman, Susan A.; Koltun, Maria; Blundell, Scott; Campbell, Anna; Pouwer, Rebecca H.; Quinn, Ronald J.; Beattie, Karren D.; Healy, Peter C.; Davis, Rohan A.
Journal:
Organic & biomolecular chemistry
Issue:
Volume 13:Issue 5(2015)
Page Start:
1558
Record Type:
Journal Article
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9. Synthesis and profiling of benzylmorpholine 1, 2, 4, 5-tetraoxane analogue N205: Towards tetraoxane scaffolds with potential for single dose cure of malaria. Issue 11 (15th July 2018)

Authors:
O' Neill, Paul M.; Stocks, Paul A.; Sabbani, Sunil; Roberts, Natalie L.; Amewu, Richard K.; Shore, Emma R.; Aljayyoussi, Ghaith; Angulo-Barturén, Iñigo; Belén, María; Jiménez-Díaz, ; Bazaga, Santiago Ferrer; Martínez, María Santos; Campo, Brice; Sharma, Raman; Charman, Susan A.; Ryan, Eileen; Che...
Journal:
Bioorganic & medicinal chemistry
Issue:
Volume 26:Issue 11(2018)
Page Start:
2996
Record Type:
Journal Article
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10. Systematic evaluation of structure–property relationships and pharmacokinetics in 6-(hetero)aryl-substituted matched pair analogs of amiloride and 5-(N, N-hexamethylene)amiloride. (1st May 2021)

Authors:
Buckley, Benjamin J.; Aboelela, Ashraf; Majed, Hiwa; Bujaroski, Richard S.; White, Karen L.; Powell, Andrew K.; Wang, Wen; Katneni, Kasiram; Saunders, Jessica; Shackleford, David M.; Charman, Susan A.; Cook, Gregory M.; Kelso, Michael J.; Ranson, Marie
Journal:
Bioorganic & medicinal chemistry
Issue:
Volume 37(2021)
Page Start:
Record Type:
Journal Article
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