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Author/Creator Chang, Jae H.

1. Characterizing the in vitro species differences in N-glucuronidation of a potent pan-PIM inhibitor GNE-924 containing a 3, 5-substituted 6-azaindazole. (3rd October 2018)

Authors:
Lin, Molly; Ly, Justin; Takahashi, Ryan; Chen, John; Deese, Alan; Robinson, Sarah J.; Kolesnikov, Aleksandr; Wong, Susan; Wang, Xiaojing; Chang, Jae H.
Journal:
Xenobiotica
Issue:
Volume 48:Number 10(2018:Oct.)
Page Start:
1021
Record Type:
Journal Article
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2. Discovery of 3, 5-substituted 6-azaindazoles as potent pan-Pim inhibitors. Issue 22 (15th November 2015)

Authors:
Hu, Huiyong; Wang, Xiaojing; Chan, Grace Ka Yan; Chang, Jae H.; Do, Steven; Drummond, Jake; Ebens, Allen; Lee, Wendy; Ly, Justin; Lyssikatos, Joseph P.; Murray, Jeremy; Moffat, John G.; Chao, Qi; Tsui, Vickie; Wallweber, Heidi; Kolesnikov, Aleksandr
Journal:
Bioorganic & medicinal chemistry letters
Issue:
Volume 25:Issue 22(2015)
Page Start:
5258
Record Type:
Journal Article
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3. Discovery of a C-8 hydroxychromene as a potent degrader of estrogen receptor alpha with improved rat oral exposure over GDC-0927. Issue 16 (15th August 2019)

Authors:
Labadie, Sharada S.; Li, Jun; Blake, Robert A.; Chang, Jae H.; Goodacre, Simon; Hartman, Steven J.; Liang, Weiling; Kiefer, James R.; Kleinheinz, Tracy; Lai, Tommy; Liao, Jiangpeng; Ortwine, Daniel F.; Mody, Vidhi; Ray, Nicholas C.; Roussel, Fabien; Vinogradova, Maia; Yeap, Siew Kuen; Zhang, Biro...
Journal:
Bioorganic & medicinal chemistry letters
Issue:
Volume 29:Issue 16(2019)
Page Start:
2090
Record Type:
Journal Article
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5. Unexpected equivalent potency of a constrained chromene enantiomeric pair rationalized by co-crystal structures in complex with estrogen receptor alpha. Issue 7 (1st April 2019)

Authors:
Zhang, Birong; Kiefer, James R.; Blake, Robert A.; Chang, Jae H.; Hartman, Steven; Ingalla, Ellen Rei; Kleinheinz, Tracy; Mody, Vidhi; Nannini, Michelle; Ortwine, Daniel F.; Ran, Yingqing; Sambrone, Amy; Sampath, Deepak; Vinogradova, Maia; Zhong, Yu; Nwachukwu, Jerome C.; Nettles, Kendall W.; Lai...
Journal:
Bioorganic & medicinal chemistry letters
Issue:
Volume 29:Issue 7(2019)
Page Start:
905
Record Type:
Journal Article
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