1. Efficacy of mGlu2‐positive allosteric modulators alone and in combination with levetiracetam in the mouse 6 Hz model of psychomotor seizures. (6th February 2017) Authors: Metcalf, Cameron S.; Klein, Brian D.; Smith, Misty D.; Pruess, Tim; Ceusters, Marc; Lavreysen, Hilde; Pype, Stefan; Van Osselaer, Nancy; Twyman, Roy; White, H. Steve Journal: Epilepsia Issue: Volume 58:issue 3(2017) Page Start: 484 Record Type: Journal Article View Content: Available online (eLD content is only available in our Reading Rooms) ↗
2. P2X7 receptor antagonism reduces the severity of spontaneous seizures in a chronic model of temporal lobe epilepsy. (June 2016) Authors: Amhaoul, Halima; Ali, Idrish; Mola, Marco; Van Eetveldt, Annemie; Szewczyk, Krystyna; Missault, Stephan; Bielen, Kenny; Kumar-Singh, Samir; Rech, Jason; Lord, Brian; Ceusters, Marc; Bhattacharya, Anindya; Dedeurwaerdere, Stefanie Journal: Neuropharmacology Issue: Volume 105(2016) Page Start: 175 Record Type: Journal Article View Content: Available online (eLD content is only available in our Reading Rooms) ↗
3. Potent and selective pharmacodynamic synergy between the metabotropic glutamate receptor subtype 2–positive allosteric modulator JNJ‐46356479 and levetiracetam in the mouse 6‐Hz (44‐mA) model. (23rd January 2018) Authors: Metcalf, Cameron S.; Klein, Brian D.; Smith, Misty D.; Ceusters, Marc; Lavreysen, Hilde; Pype, Stefan; Van Osselaer, Nancy; Twyman, Roy; White, H. Steve Journal: Epilepsia Issue: Volume 59:issue 3(2018) Page Start: 724 Record Type: Journal Article View Content: Available online (eLD content is only available in our Reading Rooms) ↗
4. P2X7 receptor antagonism reduces the severity of spontaneous seizures in a chronic model of temporal lobe epilepsy. (June 2016) Authors: Amhaoul, Halima; Ali, Idrish; Mola, Marco; Van Eetveldt, Annemie; Szewczyk, Krystyna; Missault, Stephan; Bielen, Kenny; Kumar-Singh, Samir; Rech, Jason; Lord, Brian; Ceusters, Marc; Bhattacharya, Anindya; Dedeurwaerdere, Stefanie Journal: Neuropharmacology Issue: Volume 105(2016) Page Start: 175 Record Type: Journal Article View Content: Available online (eLD content is only available in our Reading Rooms) ↗
5. Clinical pharmacokinetics, pharmacodynamics, safety, and tolerability of JNJ-54175446, a brain permeable P2X7 antagonist, in a randomised single-ascending dose study in healthy participants. (December 2018) Authors: Timmers, Maarten; Ravenstijn, Paulien; Xi, Liwen; Triana-Baltzer, Gallen; Furey, Maura; Van Hemelryck, Sandy; Biewenga, Jeike; Ceusters, Marc; Bhattacharya, Anindya; van den Boer, Maarten; van Nueten, Luc; de Boer, Peter Journal: Journal of psychopharmacology Issue: Volume 32:Number 12(2018) Page Start: 1341 Record Type: Journal Article View Content: Available online (eLD content is only available in our Reading Rooms) ↗
6. Increased uptake of the P2X7 receptor radiotracer 18F‐JNJ‐64413739 in the brain and peripheral organs according to the severity of status epilepticus in male mice. Issue 2 (27th December 2022) Authors: Morgan, James; Moreno, Oscar; Alves, Mariana; Baz, Zuriñe; Menéndez Méndez, Aida; Leister, Hanna; Melia, Ciara; Smith, Jonathon; Visekruna, Alexander; Nicke, Annette; Bhattacharya, Anindya; Ceusters, Marc; Henshall, David C.; Gómez‐Vallejo, Vanessa; Llop, Jordi; Engel, Tobias Journal: Epilepsia Issue: Volume 64:Issue 2(2023) Page Start: 511 Record Type: Journal Article View Content: Available online (eLD content is only available in our Reading Rooms) ↗