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Author/Creator Carvalho, Andrew

1. Discovery of CYR715: A novel carboxylic acid-containing soluble guanylate cyclase stimulator. (15th May 2021)

Authors:
Rennie, Glen R.; Barden, Timothy C.; Bernier, Sylvie G.; Carvalho, Andrew; Deming, Renee; Germano, Peter; Hudson, Colleen; Im, G-Yoon J.; Iyengar, Rajesh R.; Jia, Lei; Jung, Joon; Kim, Elise; Lee, Thomas W.-H.; Mermerian, Ara; Moore, Joel; Nakai, Takashi; Perl, Nicholas R.; Tobin, Jenny; Zimmer, ...
Journal:
Bioorganic & medicinal chemistry letters
Issue:
Volume 40(2021)
Page Start:
Record Type:
Journal Article
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2. P10 - Use of microbial biotransformation to produce scalable quantities of a glucuronidated metabolite of the clinical-stage soluble guanylate cyclase inhibitor praliciguat. (2020)

Authors:
Shanu-Wilson, Julia; Steele, Jonathan; Phipps, Richard; Manohar, Ravi; Karunakaran, Deepa; Borowik, Alicja; Scheffler, Frank; Evans, Liam; Carvalho, Andrew; Banijamali, Ali
Journal:
Drug metabolism and pharmacokinetics
Issue:
Volume 35(2020)Supplement 1
Page Start:
S25
Record Type:
Journal Article
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3. Quantitative mass balance, tissue distribution, pharmacokinetics and biotransformation pathway of praliciguat, a clinical-stage sgc stimulator, after oral administration in rats. Issue 1 (January 2019)

Authors:
Banijamali, Ali; Carvalho, Andrew; Wakefield, James; Germano, Peter; Ribadeneira, Maria; Barden, Timothy; Zimmer, Daniel; Masferrer, Jaime; Profy, Albert; Currie, Mark; Milne, Todd; Germano, Peter
Journal:
Drug metabolism and pharmacokinetics
Issue:
Volume 34:Issue 1(2019)Supplement
Page Start:
S56
Record Type:
Journal Article
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Available online (eLD content is only available in our Reading Rooms) ↗