1. Conjugation of hydrophobic moieties enhances potency of antisense oligonucleotides in the muscle of rodents and non-human primates. Issue 12 (11th May 2019) Authors: Østergaard, Michael E; Jackson, Michaela; Low, Audrey; E. Chappell, Alfred; G. Lee, Richard; Peralta, Rachel Q; Yu, Jinghua; Kinberger, Garth A; Dan, Amy; Carty, Rick; Tanowitz, Michael; Anderson, Patrick; Kim, Tae-Won; Fradkin, Linda; Mullick, Adam E; Murray, Sue; Rigo, Frank; Prakash,... Journal: Nucleic acids research Issue: Volume 47:Issue 12(2019) Page Start: 6045 Record Type: Journal Article View Content: Available online (eLD content is only available in our Reading Rooms) ↗
2. Targeted delivery of antisense oligonucleotides to hepatocytes using triantennary N-acetyl galactosamine improves potency 10-fold in mice. Issue 13 (3rd July 2014) Authors: Prakash, Thazha P.; Graham, Mark J.; Yu, Jinghua; Carty, Rick; Low, Audrey; Chappell, Alfred; Schmidt, Karsten; Zhao, Chenguang; Aghajan, Mariam; Murray, Heather F.; Riney, Stan; Booten, Sheri L.; Murray, Susan F.; Gaus, Hans; Crosby, Jeff; Lima, Walt F.; Guo, Shuling; Monia, Brett P.; Swayze, Er... Journal: Nucleic acids research Issue: Volume 42:Issue 13(2014) Page Start: 8796 Record Type: Journal Article View Content: Available online (eLD content is only available in our Reading Rooms) ↗