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Author/Creator Byers, Frank W.

1. Challenges in the development of an M4 PAM preclinical candidate: The discovery, SAR, and biological characterization of a series of azetidine-derived tertiary amides. Issue 23 (1st December 2017)

Authors:
Tarr, James C.; Wood, Michael R.; Noetzel, Meredith J.; Melancon, Bruce J.; Lamsal, Atin; Luscombe, Vincent B.; Rodriguez, Alice L.; Byers, Frank W.; Chang, Sichen; Cho, Hyekyung P.; Engers, Darren W.; Jones, Carrie K.; Niswender, Colleen M.; Wood, Michael W.; Brandon, Nicholas J.; Duggan, Mark E...
Journal:
Bioorganic & medicinal chemistry letters
Issue:
Volume 27:Issue 23(2017)
Page Start:
5179
Record Type:
Journal Article
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2. Challenges in the development of an M4 PAM preclinical candidate: The discovery, SAR, and in vivo characterization of a series of 3-aminoazetidine-derived amides. Issue 13 (1st July 2017)

Authors:
Tarr, James C.; Wood, Michael R.; Noetzel, Meredith J.; Bertron, Jeanette L.; Weiner, Rebecca L.; Rodriguez, Alice L.; Lamsal, Atin; Byers, Frank W.; Chang, Sichen; Cho, Hyekyung P.; Jones, Carrie K.; Niswender, Colleen M.; Wood, Michael W.; Brandon, Nicholas J.; Duggan, Mark E.; Conn, P. Jeffrey...
Journal:
Bioorganic & medicinal chemistry letters
Issue:
Volume 27:Issue 13(2017)
Page Start:
2990
Record Type:
Journal Article
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3. Corrigendum to "Challenges in the development of an M4 PAM preclinical candidate: The discovery, SAR, and biological characterization of a series of azetidine-derived tertiary amides" [Bioorg. Med. Chem. Lett. 27(23) (2017) 5179–5184]. Issue 17 (15th September 2018)

Authors:
Tarr, James C.; Wood, Michael R.; Noetzel, Meredith J.; Melancon, Bruce J.; Lamsal, Atin; Luscombe, Vincent B.; Rodriguez, Alice L.; Byers, Frank W.; Chang, Sichen; Cho, Hyekyung P.; Engers, Darren W.; Jones, Carrie K.; Niswender, Colleen M.; Wood, Michael W.; Brandon, Nicholas J.; Duggan, Mark E...
Journal:
Bioorganic & medicinal chemistry letters
Issue:
Volume 28:Issue 17(2018)
Page Start:
3014
Record Type:
Journal Article
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4. Discovery of 6-(pyrimidin-5-ylmethyl)quinoline-8-carboxamide negative allosteric modulators of metabotropic glutamate receptor subtype 5. Issue 10 (1st June 2018)

Authors:
Felts, Andrew S.; Rodriguez, Alice L.; Morrison, Ryan D.; Blobaum, Anna L.; Byers, Frank W.; Daniels, J. Scott; Niswender, Colleen M.; Conn, P. Jeffrey; Lindsley, Craig W.; Emmitte, Kyle A.
Journal:
Bioorganic & medicinal chemistry letters
Issue:
Volume 28:Issue 10(2018)
Page Start:
1679
Record Type:
Journal Article
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5. Discovery of imidazo[1, 2-a]-, [1, 2, 4]triazolo[4, 3-a]-, and [1, 2, 4]triazolo[1, 5-a]pyridine-8-carboxamide negative allosteric modulators of metabotropic glutamate receptor subtype 5. Issue 21 (1st November 2017)

Authors:
Felts, Andrew S.; Rodriguez, Alice L.; Morrison, Ryan D.; Bollinger, Katrina A.; Venable, Daryl F.; Blobaum, Anna L.; Byers, Frank W.; Thompson Gray, Analisa; Daniels, J. Scott; Niswender, Colleen M.; Jones, Carrie K.; Conn, P. Jeffrey; Lindsley, Craig W.; Emmitte, Kyle A.
Journal:
Bioorganic & medicinal chemistry letters
Issue:
Volume 27:Issue 21(2017)
Page Start:
4858
Record Type:
Journal Article
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6. Further optimization of the M5 NAM MLPCN probe ML375: Tactics and challenges. Issue 3 (1st February 2015)

Authors:
Kurata, Haruto; Gentry, Patrick R.; Kokubo, Masaya; Cho, Hyekyung P.; Bridges, Thomas M.; Niswender, Colleen M.; Byers, Frank W.; Wood, Michael R.; Daniels, J. Scott; Conn, P. Jeffrey; Lindsley, Craig W.
Journal:
Bioorganic & medicinal chemistry letters
Issue:
Volume 25:Issue 3(2015)
Page Start:
690
Record Type:
Journal Article
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7. N-Alkylpyrido[1′, 2′:1, 5]pyrazolo-[4, 3-d]pyrimidin-4-amines: A new series of negative allosteric modulators of mGlu1/5 with CNS exposure in rodents. Issue 8 (15th April 2016)

Authors:
Felts, Andrew S.; Rodriguez, Alice L.; Morrison, Ryan D.; Venable, Daryl F.; Blobaum, Anna L.; Byers, Frank W.; Daniels, J. Scott; Niswender, Colleen M.; Jones, Carrie K.; Conn, P. Jeffrey; Lindsley, Craig W.; Emmitte, Kyle A.
Journal:
Bioorganic & medicinal chemistry letters
Issue:
Volume 26:Issue 8(2016)
Page Start:
1894
Record Type:
Journal Article
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8. Optimization of M4 positive allosteric modulators (PAMs): The discovery of VU0476406, a non-human primate in vivo tool compound for translational pharmacology. Issue 11 (1st June 2017)

Authors:
Melancon, Bruce J.; Wood, Michael R.; Noetzel, Meredith J.; Nance, Kellie D.; Engelberg, Eileen M.; Han, Changho; Lamsal, Atin; Chang, Sichen; Cho, Hyekyung P.; Byers, Frank W.; Bubser, Michael; Jones, Carrie K.; Niswender, Colleen M.; Wood, Michael W.; Engers, Darren W.; Wu, Dedong; Brandon, Nic...
Journal:
Bioorganic & medicinal chemistry letters
Issue:
Volume 27:Issue 11(2017)
Page Start:
2296
Record Type:
Journal Article
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9. Use of a novel rapid and resource‐efficient cassette dosing approach to determine the pharmacokinetics and CNS distribution of small molecule 7‐transmembrane receptor allosteric modulators in rat. Issue 6 (1st September 2014)

Authors:
Bridges, Thomas. M.; Morrison, Ryan D.; Byers, Frank W.; Luo, Shuanghui; Scott Daniels, J.
Journal:
Pharmacology research & perspectives
Issue:
Volume 2:Issue 6(2014)
Page Start:
n/a
Record Type:
Journal Article
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