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Author/Creator Brown, Alastair J.H.

1. A phase 1b/2a multicenter study of the safety and preliminary pharmacodynamic effects of selective muscarinic M1 receptor agonist HTL0018318 in patients with mild‐to‐moderate Alzheimer's disease. Issue 1 (23rd February 2022)

Authors:
Nathan, Pradeep J.; Millais, S. Babli; Godwood, Alex; Dewit, Odile; Cross, David M.; Liptrot, Janet; Ruparelia, Bharat; Jones, Stephen Paul; Bakker, Geor; Maruff, Paul T.; Light, Gregory A.; Brown, Alastair J.H.; Weir, Malcolm Peter; Congreve, Miles; Tasker, Tim
Journal:
Alzheimer's & dementia
Issue:
Volume 8:Issue 1(2022)
Page Start:
n/a
Record Type:
Journal Article
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2. Cholinergic muscarinic M1 and M4 receptors as therapeutic targets for cognitive, behavioural, and psychological symptoms in psychiatric and neurological disorders. Issue 12 (December 2019)

Authors:
Erskine, Daniel; Taylor, John-Paul; Bakker, Geor; Brown, Alastair J.H.; Tasker, Tim; Nathan, Pradeep J.
Journal:
Drug discovery today
Issue:
Volume 24:Issue 12(2019)
Page Start:
2307
Record Type:
Journal Article
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4. Identification of a novel allosteric GLP-1R antagonist HTL26119 using structure- based drug design. Issue 20 (15th October 2019)

Authors:
O'Brien, Alistair; Andrews, Stephen P.; Baig, Asma H.; Bortolato, Andrea; Brown, Alastair J.H.; Brown, Giles A.; Brown, Sue H.; Christopher, John A.; Congreve, Miles; Cooke, Robert M.; De Graaf, Chris; Errey, James C.; Fieldhouse, Charlotte; Jazayeri, Ali; Marshall, Fiona H.; Mason, Jonathan S.; ...
Journal:
Bioorganic & medicinal chemistry letters
Issue:
Volume 29:Issue 20(2019)
Page Start:
Record Type:
Journal Article
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5. Identification of a novel allosteric GLP-1R antagonist HTL26119 using structure-based drug design. Issue 20 (15th October 2019)

Authors:
O'Brien, Alistair; Andrews, Stephen P.; Baig, Asma H.; Bortolato, Andrea; Brown, Alastair J.H.; Brown, Giles A.; Brown, Sue H.; Christopher, John A.; Congreve, Miles; Cooke, Robert M.; De Graaf, Chris; Errey, James C.; Fieldhouse, Charlotte; Jazayeri, Ali; Marshall, Fiona H.; Mason, Jonathan S.; ...
Journal:
Bioorganic & medicinal chemistry letters
Issue:
Volume 29:Issue 20(2019)
Page Start:
Record Type:
Journal Article
View Content:
Available online (eLD content is only available in our Reading Rooms) ↗