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Author/Creator Brassil, Patrick

1. Development of Gut-Selective Pan-Janus Kinase Inhibitor TD-1473 for Ulcerative Colitis: A Translational Medicine Programme. (11th March 2020)

Authors:
Sandborn, William J; Nguyen, Deanna D; Beattie, David T; Brassil, Patrick; Krey, Whitney; Woo, Jacky; Situ, Eva; Sana, Reuben; Sandvik, Erik; Pulido-Rios, M Teresa; Bhandari, Raj; Leighton, Jonathan A; Ganeshappa, Ravi; Boyle, David L; Abhyankar, Brihad; Kleinschek, Melanie A; Graham, Richard A; ...
Journal:
Journal of Crohn's and colitis
Issue:
Volume 14:Number 9(2020)
Page Start:
1202
Record Type:
Journal Article
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2. Gut-Selective Design of Orally Administered Izencitinib (TD-1473) Limits Systemic Exposure and Effects of Janus Kinase Inhibition in Nonclinical Species. (4th February 2022)

Authors:
Hardwick, Rhiannon N; Brassil, Patrick; Badagnani, Ilaria; Perkins, Kimberly; Obedencio, Glenmar P; Kim, Andrea S; Conner, Michael W; Bourdet, David L; Harstad, Eric B
Journal:
Toxicological sciences
Issue:
Volume 186:Number 2(2022)
Page Start:
323
Record Type:
Journal Article
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3. Heteroarylamide smoothened inhibitors: Discovery of N-[2, 4-dimethyl-5-(1-methylimidazol-4-yl)phenyl]-4-(2-pyridylmethoxy)benzamide (AZD8542) and N-[5-(1H-imidazol-2-yl)-2, 4-dimethyl-phenyl]-4-(2- pyridylmethoxy)benzamide (AZD7254). Issue 2 (15th January 2020)

Authors:
Yang, Bin; Hird, Alexander W.; Bodnarchuk, Michael S.; Zheng, Xiaolan; Dakin, Les; Su, Qibin; Daly, Kevin; Godin, Robert; Hattersley, Maureen M.; Brassil, Patrick; Redmond, Sean; John Russell, Daniel; Janetka, James W.
Journal:
Bioorganic & medicinal chemistry
Issue:
Volume 28:Issue 2(2020)
Page Start:
Record Type:
Journal Article
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