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Author/Creator Bozarth, Jeffrey M.

2. Macrocyclic inhibitors of Factor XIa: Discovery of alkyl-substituted macrocyclic amide linkers with improved potency. Issue 16 (15th August 2017)

Authors:
Corte, James R.; Yang, Wu; Fang, Tianan; Wang, Yufeng; Osuna, Honey; Lai, Amy; Ewing, William R.; Rossi, Karen A.; Myers, Joseph E.; Sheriff, Steven; Lou, Zhen; Zheng, Joanna J.; Harper, Timothy W.; Bozarth, Jeffrey M.; Wu, Yiming; Luettgen, Joseph M.; Seiffert, Dietmar A.; Quan, Mimi L.; Wexler,...
Journal:
Bioorganic & medicinal chemistry letters
Issue:
Volume 27:Issue 16(2017)
Page Start:
3833
Record Type:
Journal Article
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3. Milvexian, an orally bioavailable, small‐molecule, reversible, direct inhibitor of factor XIa: In vitro studies and in vivo evaluation in experimental thrombosis in rabbits. (24th November 2021)

Authors:
Wong, Pancras C.; Crain, Earl J.; Bozarth, Jeffrey M.; Wu, Yiming; Dilger, Andrew K.; Wexler, Ruth R.; Ewing, William R.; Gordon, David; Luettgen, Joseph M.
Journal:
Journal of thrombosis and haemostasis
Issue:
Volume 20:Number 2(2022)
Page Start:
399
Record Type:
Journal Article
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4. Neutral macrocyclic factor VIIa inhibitors. Issue 12 (15th June 2017)

Authors:
Wurtz, Nicholas R.; Parkhurst, Brandon L.; DeLucca, Indawati; Glunz, Peter W.; Jiang, Wen; Zhang, Xiaojun; Cheney, Daniel L.; Bozarth, Jeffrey M.; Rendina, Alan R.; Wei, Anzhi; Harper, Tim; Luettgen, Joseph M.; Wu, Yiming; Wong, Pancras C.; Seiffert, Dietmar A.; Wexler, Ruth R.; Priestley, E. Scott
Journal:
Bioorganic & medicinal chemistry letters
Issue:
Volume 27:Issue 12(2017)
Page Start:
2650
Record Type:
Journal Article
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5. Novel phenylalanine derived diamides as Factor XIa inhibitors. Issue 2 (15th January 2016)

Authors:
Smith, Leon M.; Orwat, Michael J.; Hu, Zilun; Han, Wei; Wang, Cailan; Rossi, Karen A.; Gilligan, Paul J.; Pabbisetty, Kumar B.; Osuna, Honey; Corte, James R.; Rendina, Alan R.; Luettgen, Joseph M.; Wong, Pancras C.; Narayanan, Ranga; Harper, Timothy W.; Bozarth, Jeffrey M.; Crain, Earl J.; Wei, A...
Journal:
Bioorganic & medicinal chemistry letters
Issue:
Volume 26:Issue 2(2016)
Page Start:
472
Record Type:
Journal Article
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6. Orally bioavailable amine-linked macrocyclic inhibitors of factor XIa. Issue 4 (15th February 2020)

Authors:
Fang, Tianan; Corte, James R.; Gilligan, Paul J.; Jeon, Yoon; Osuna, Honey; Rossi, Karen A.; Myers, Joseph E.; Sheriff, Steven; Lou, Zhen; Zheng, Joanna J.; Harper, Timothy W.; Bozarth, Jeffrey M.; Wu, Yiming; Luettgen, Joseph M.; Seiffert, Dietmar A.; Wexler, Ruth R.; Lam, Patrick Y.S.
Journal:
Bioorganic & medicinal chemistry letters
Issue:
Volume 30:Issue 4(2020)
Page Start:
Record Type:
Journal Article
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7. Pyridazine and pyridazinone derivatives as potent and selective factor XIa inhibitors. Issue 6 (1st April 2018)

Authors:
Hu, Zilun; Wang, Cailan; Han, Wei; Rossi, Karen A.; Bozarth, Jeffrey M.; Wu, Yiming; Sheriff, Steven; Myers, Joseph E.; Luettgen, Joseph M.; Seiffert, Dietmar A.; Wexler, Ruth R.; Quan, Mimi L.
Journal:
Bioorganic & medicinal chemistry letters
Issue:
Volume 28:Issue 6(2018)
Page Start:
987
Record Type:
Journal Article
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8. Pyridine and pyridinone-based factor XIa inhibitors. Issue 4 (15th February 2015)

Authors:
Corte, James R.; Fang, Tianan; Hangeland, Jon J.; Friends, Todd J.; Rendina, Alan R.; Luettgen, Joseph M.; Bozarth, Jeffrey M.; Barbera, Frank A.; Rossi, Karen A.; Wei, Anzhi; Ramamurthy, Vidhyashankar; Morin, Paul E.; Seiffert, Dietmar A.; Wexler, Ruth R.; Quan, Mimi L.
Journal:
Bioorganic & medicinal chemistry letters
Issue:
Volume 25:Issue 4(2015)
Page Start:
925
Record Type:
Journal Article
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9. Structure based design of macrocyclic factor XIa inhibitors: Discovery of cyclic P1 linker moieties with improved oral bioavailability. Issue 19 (1st October 2019)

Authors:
Clark, Charles G.; Rossi, Karen A.; Corte, James R.; Fang, Tianan; Smallheer, Joanne M.; De Lucca, Indawati; Nirschl, David S.; Orwat, Michael J.; Pinto, Donald J.P.; Hu, Zilun; Wang, Yufeng; Yang, Wu; Jeon, Yoon; Ewing, William R.; Myers, Joseph E.; Sheriff, Steven; Lou, Zhen; Bozarth, Jeffrey M...
Journal:
Bioorganic & medicinal chemistry letters
Issue:
Volume 29:Issue 19(2019)
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Record Type:
Journal Article
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10. Structure-based design of inhibitors of coagulation factor XIa with novel P1 moieties. Issue 7 (1st April 2015)

Authors:
Pinto, Donald J.P.; Smallheer, Joanne M.; Corte, James R.; Austin, Erin J.D.; Wang, Cailan; Fang, Tianan; Smith, Leon M.; Rossi, Karen A.; Rendina, Alan R.; Bozarth, Jeffrey M.; Zhang, Ge; Wei, Anzhi; Ramamurthy, Vidhyashankar; Sheriff, Steven; Myers, Joseph E.; Morin, Paul E.; Luettgen, Joseph M...
Journal:
Bioorganic & medicinal chemistry letters
Issue:
Volume 25:Issue 7(2015)
Page Start:
1635
Record Type:
Journal Article
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