1. Chirality matters: stereo-defined phosphorothioate linkages at the termini of small interfering RNAs improve pharmacology in vivo. Issue 3 (15th July 2021) Authors: Jahns, Hartmut; Taneja, Nate; Willoughby, Jennifer L S; Akabane-Nakata, Masaaki; Brown, Christopher R; Nguyen, Tuyen; Bisbe, Anna; Matsuda, Shigeo; Hettinger, Matt; Manoharan, Rajar M; Rajeev, Kallanthottathil G; Maier, Martin A; Zlatev, Ivan; Charisse, Klaus; Egli, Martin; Manoharan, Muthiah Journal: Nucleic acids research Issue: Volume 50:Issue 3(2022) Page Start: 1221 Record Type: Journal Article View Content: Available online (eLD content is only available in our Reading Rooms) ↗
2. Small circular interfering RNAs (sciRNAs) as a potent therapeutic platform for gene-silencing. Issue 18 (11th September 2021) Authors: Jahns, Hartmut; Degaonkar, Rohan; Podbevsek, Peter; Gupta, Swati; Bisbe, Anna; Aluri, Krishna; Szeto, John; Kumar, Pawan; LeBlanc, Sarah; Racie, Tim; Brown, Christopher R; Castoreno, Adam; Guenther, Dale C; Jadhav, Vasant; Maier, Martin A; Plavec, Janez; Egli, Martin; Manoharan, Mu... Journal: Nucleic acids research Issue: Volume 49:Issue 18(2021) Page Start: 10250 Record Type: Journal Article View Content: Available online (eLD content is only available in our Reading Rooms) ↗
3. Structural basis for the synergy of 4′- and 2′-modifications on siRNA nuclease resistance, thermal stability and RNAi activity. Issue 16 (11th August 2018) Authors: Harp, Joel M; Guenther, Dale C; Bisbe, Anna; Perkins, Lydia; Matsuda, Shigeo; Bommineni, Gopal R; Zlatev, Ivan; Foster, Donald J; Taneja, Nate; Charisse, Klaus; Maier, Martin A; Rajeev, Kallanthottathil G; Manoharan, Muthiah; Egli, Martin Journal: Nucleic acids research Issue: Volume 46:Issue 16(2018) Page Start: 8090 Record Type: Journal Article View Content: Available online (eLD content is only available in our Reading Rooms) ↗