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Author/Creator Bertron, Jeanette L.

1. Challenges in the development of an M4 PAM preclinical candidate: The discovery, SAR, and in vivo characterization of a series of 3-aminoazetidine-derived amides. Issue 13 (1st July 2017)

Authors:
Tarr, James C.; Wood, Michael R.; Noetzel, Meredith J.; Bertron, Jeanette L.; Weiner, Rebecca L.; Rodriguez, Alice L.; Lamsal, Atin; Byers, Frank W.; Chang, Sichen; Cho, Hyekyung P.; Jones, Carrie K.; Niswender, Colleen M.; Wood, Michael W.; Brandon, Nicholas J.; Duggan, Mark E.; Conn, P. Jeffrey...
Journal:
Bioorganic & medicinal chemistry letters
Issue:
Volume 27:Issue 13(2017)
Page Start:
2990
Record Type:
Journal Article
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Available online (eLD content is only available in our Reading Rooms) ↗

3. Optimization of the choline transporter (CHT) inhibitor ML352: Development of VU6001221, an improved in vivo tool compound. Issue 19 (1st October 2016)

Authors:
Bertron, Jeanette L.; Ennis, Elizabeth A.; Tarr, Christopher J.; Wright, Jane; Dickerson, Jonathan W.; Locuson, Charles W.; Blobaum, Anna L.; Rook, Jerri M.; Blakely, Randy D.; Lindsley, Craig W.
Journal:
Bioorganic & medicinal chemistry letters
Issue:
Volume 26:Issue 19(2016)
Page Start:
4637
Record Type:
Journal Article
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4. The discovery of VU0486846: steep SAR from a series of M1 PAMs based on a novel benzomorpholine core. Issue 12 (1st July 2018)

Authors:
Bertron, Jeanette L.; Cho, Hyekyung P.; Garcia-Barrantes, Pedro M.; Panarese, Joseph D.; Salovich, James M.; Nance, Kellie D.; Engers, Darren W.; Rook, Jerri M.; Blobaum, Anna L.; Niswender, Colleen M.; Stauffer, Shaun R.; Conn, P. Jeffrey; Lindsley, Craig W.
Journal:
Bioorganic & medicinal chemistry letters
Issue:
Volume 28:Issue 12(2018)
Page Start:
2175
Record Type:
Journal Article
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5. VU6005806/AZN-00016130, an advanced M4 positive allosteric modulator (PAM) profiled as a potential preclinical development candidate. Issue 14 (15th July 2019)

Authors:
Engers, Darren W.; Melancon, Bruce J.; Gregro, Allison R.; Bertron, Jeanette L.; Bollinger, Sean R.; Felts, Andrew S.; Konkol, Leah C.; Wood, Michael R.; Bollinger, Katrina A.; Luscombe, Vincent B.; Rodriguez, Alice L.; Jones, Carrie K.; Bubser, Michael; Yohn, Samantha E.; Wood, Michael W.; Brand...
Journal:
Bioorganic & medicinal chemistry letters
Issue:
Volume 29:Issue 14(2019)
Page Start:
1714
Record Type:
Journal Article
View Content:
Available online (eLD content is only available in our Reading Rooms) ↗