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You searched for: Author/Creator Barden, Timothy C.- Barden, Timothy C. [remove] 2
- 572 1
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- Bioorganic chemistry -- Periodicals 1
- Drug development -- Periodicals 1
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- Soluble guanylate cyclase -- sGC -- sGC stimulator -- Nitric oxide -- CYR715 1
- absorption -- cGMP -- excretion -- mass balance -- metabolism -- nitric oxide -- pharmacokinetics -- praliciguat -- QWBA -- sGC 1
- sGC soluble guanylate cyclase -- DETA-NO diethylenetriamine NONOate -- AUC area under the curve -- RLM rat liver microsome -- HLM human liver microsome -- MAP mean arterial pressure -- SAR structure–activity relationship -- TEA triethyl amine -- NaH sodium hydride -- THF tetrahydrofuran -- SNAr nucleophilic aromatic substitution -- POCl3 phosphorus(V) oxide chloride -- AG acyl glucuronide conjugate -- IDT idiosyncratic drug toxicity -- ODQ 1H-[1, 2, 4]oxadiazolo[4, 3-a]quinoxalin-1-one -- CYP cytochrome P450 isoenzymes 1