1. Discovery of a 2′-fluoro-2′-C-methyl C-nucleotide HCV polymerase inhibitor and a phosphoramidate prodrug with favorable properties. Issue 8 (15th April 2017) Authors: Kirschberg, Thorsten A.; Metobo, Sammy; Clarke, Michael O.; Aktoudianakis, Vangelis; Babusis, Darius; Barauskas, Ona; Birkus, Gabriel; Butler, Thomas; Byun, Daniel; Chin, Gregory; Doerffler, Edward; Edwards, Thomas E.; Fenaux, Martijn; Lee, Rick; Lew, Willard; Mish, Michael R.; Murakami, Eisuke; ... Journal: Bioorganic & medicinal chemistry letters Issue: Volume 27:Issue 8(2017) Page Start: 1840 Record Type: Journal Article View Content: Available online (eLD content is only available in our Reading Rooms) ↗
2. Discovery of the pan-genotypic hepatitis C virus NS3/4A protease inhibitor voxilaprevir (GS-9857): A component of Vosevi®. Issue 16 (15th August 2019) Authors: Taylor, James G.; Zipfel, Sheila; Ramey, Kyla; Vivian, Randy; Schrier, Adam; Karki, Kapil K.; Katana, Ashley; Kato, Darryl; Kobayashi, Tetsuya; Martinez, Ruben; Sangi, Michael; Siegel, Dustin; Tran, Chinh V.; Yang, Zheng-Yu; Zablocki, Jeff; Yang, Cheng Y.; Wang, Yujin; Wang, Kelly; Chan, Katie; B... Journal: Bioorganic & medicinal chemistry letters Issue: Volume 29:Issue 16(2019) Page Start: 2428 Record Type: Journal Article View Content: Available online (eLD content is only available in our Reading Rooms) ↗
3. Discovery of β-d-2′-deoxy-2′-α-fluoro-4′-α-cyano-5-aza-7, 9-dideaza adenosine as a potent nucleoside inhibitor of respiratory syncytial virus with excellent selectivity over mitochondrial RNA and DNA polymerases. Issue 12 (15th June 2015) Authors: Clarke, Michael O.; Mackman, Richard; Byun, Daniel; Hui, Hon; Barauskas, Ona; Birkus, Gabriel; Chun, Byoung-Kwon; Doerffler, Edward; Feng, Joy; Karki, Kapil; Lee, Gary; Perron, Michel; Siegel, Dustin; Swaminathan, Swami; Lee, William Journal: Bioorganic & medicinal chemistry letters Issue: Volume 25:Issue 12(2015) Page Start: 2484 Record Type: Journal Article View Content: Available online (eLD content is only available in our Reading Rooms) ↗
4. In vitro Selection of Resistance to Sofosbuvir in HCV Replicons of Genotype-1 to -6. Issue 7 (October 2017) Authors: Xu, Simin; Doehle, Brian; Rajyaguru, Sonal; Han, Bin; Barauskas, Ona; Feng, Joy; Perry, Jason; Dvory-Sobol, Hadas; Svarovskaia, Evguenia S; Miller, Michael D; Mo, Hongmei Journal: Antiviral therapy Issue: Volume 22:Issue 7(2017) Page Start: 587 Record Type: Journal Article View Content: Available online (eLD content is only available in our Reading Rooms) ↗
5. Synthesis and biological evaluation of conformationally restricted adenine bicycloribonucleosides1. Issue 35 (21st September 2015) Authors: Hřebabecký, Hubert; Procházková, Eliška; Šála, Michal; Plačková, Pavla; Tloušťová, Eva; Barauskas, Ona; Lee, Yu-Jen; Tian, Yang; Mackman, Richard; Nencka, Radim Journal: Organic & biomolecular chemistry Issue: Volume 13:Issue 35(2015) Page Start: 9300 Record Type: Journal Article View Content: Available online (eLD content is only available in our Reading Rooms) ↗