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Author/Creator Adams, Ralph

1. Electrostatic interactions modulate the differential aggregation propensities of IgG1 and IgG4P antibodies and inform charged residue substitutions for improved developability. Issue 6 (23rd December 2019)

Authors:
Heads, James T; Lamb, Richard; Kelm, Sebastian; Adams, Ralph; Elliott, Peter; Tyson, Kerry; Topia, Sarfaraj; West, Shauna; Nan, Ruodan; Turner, Alison; Lawson, Alastair D G
Journal:
Protein engineering, design & selection
Issue:
Volume 32:Issue 6(2019)
Page Start:
277
Record Type:
Journal Article
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Available online (eLD content is only available in our Reading Rooms) ↗

2. Extending the half-life of a fab fragment through generation of a humanized anti-human serum albumin Fv domain: An investigation into the correlation between affinity and serum half-life. Issue 7 (2nd October 2016)

Authors:
Adams, Ralph; Griffin, Laura; Compson, Joanne E.; Jairaj, Mark; Baker, Terry; Ceska, Tom; West, Shauna; Zaccheo, Oliver; Davé, Emma; Lawson, Alastair DG.; Humphreys, David P.; Heywood, Sam
Journal:
MAbs
Issue:
Volume 8:Issue 7(2016)
Page Start:
1336
Record Type:
Journal Article
View Content:
Available online (eLD content is only available in our Reading Rooms) ↗

3. Fab-dsFv: A bispecific antibody format with extended serum half-life through albumin binding. Issue 7 (2nd October 2016)

Authors:
Davé, Emma; Adams, Ralph; Zaccheo, Oliver; Carrington, Bruce; Compson, Joanne E.; Dugdale, Sarah; Airey, Michael; Malcolm, Sarah; Hailu, Hanna; Wild, Gavin; Turner, Alison; Heads, James; Sarkar, Kaushik; Ventom, Andrew; Marshall, Diane; Jairaj, Mark; Kopotsha, Tim; Christodoulou, Louis; Zamacona,...
Journal:
MAbs
Issue:
Volume 8:Issue 7(2016)
Page Start:
1319
Record Type:
Journal Article
View Content:
Available online (eLD content is only available in our Reading Rooms) ↗

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